Literature search at Indiana University, Bloomington, Indiana
MEDLINE EXPRESS (R) 1990-1994 102 of 144
TI: The effects of total and partial callosal agenesis on the rotatory behavior of BALB/cCF mice.
AU: Schmidt-SL; Lent-R
AD: Instituto de Biofisica Carlos Chagas Filho, Centro de Ciencias da Saude, Universidade Federal do Rio de Janeiro, Brasil.
SO: Braz-J-Med-Biol-Res. 1991; 24(4): 417-20
ISSN: 0100-879X
PY: 1991
LA: ENGLISH
CP: BRAZIL
AB: We report a study on rotational behavior (free swim test) of 30 adult male mice of an inbred strain in which about 20% of the animals are born with callosal defects (the BALB/cCF strain). The experiment was designed to study the relationship between the development of the corpus callosum and the degree of lateralization in rotatory behavior. Most of the BALB/cCF mice (77%) were lateralized rotators. Although most animals with a normal callosal area presented individual asymmetry, there was no significant tendency for a populational asymmetry toward one side in this group. In contrast, 75% of the animals with abnormally small callosal areas were left rotators. These animals, therefore, presented not only individual asymmetry, but also a tendency for a populational asymmetry. It was concluded that disturbances in the development of the corpus callosum are related to the appearance of directional populational asymmetry in rotatory behavior.
MESH: Laterality-; Mice-; Mice,-Inbred-BALB-C; Rotation-
MESH: *Behavior,-Animal; *Corpus-Callosum-abnormalities
TG: Animal; Male; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 92370043
UD: 9211
MEDLINE EXPRESS (R) 1990-1994 103 of 144
TI: Agenesis of the corpus callosum. Its associated anomalies and syndromes with special reference to the Apert syndrome.
AU: Cohen-MM Jr; Kreiborg-S
AD: Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada.
SO: Neurosurg-Clin-N-Am. 1991 Jul; 2(3): 565-8
ISSN: 1042-3680
PY: 1991
LA: ENGLISH
CP: UNITED-STATES
AB: Agenesis of the corpus callosum may be associated with a variety of central nervous system (CNS) and non-CNS abnormalities and is known to occur in a number of specific syndromes. It can be a marker for several inherited metabolic disorders. Study of the Apert syndrome shows a recurrent pattern of CNS abnormalities, including defects of the corpus callosum and limbic structures, megalencephaly, misshapen brain, distortion ventriculomegaly, and gyral anomalies.
MESH: Adult-; Child,-Preschool; Infant-; Infant,-Newborn; Syndrome-
MESH: *Acrocephalosyndactylia-pathology; *Corpus-Callosum-abnormalities
TG: Female; Human; Male
PT: JOURNAL-ARTICLE; REVIEW; REVIEW-OF-REPORTED-CASES
AN: 92330654
UD: 9210
MEDLINE EXPRESS (R) 1990-1994 104 of 144
TI: Unusual presentation of gastroesophageal reflux with corpus callosum agenesis, cleft palate and mental retardation.
AU: Desai-BN; Joshi-SM; Malik-S; Mittal-S; Dandge-VP
AD: Department of Pediatrics, Nair Hospital, Bombay.
SO: Indian-Pediatr. 1991 Nov; 28(11): 1328-30
ISSN: 0019-6061
PY: 1991
LA: ENGLISH
CP: INDIA
MESH: Infant,-Newborn
MESH: *Abnormalities,-Multiple; *Cleft-Palate; *Corpus-Callosum-abnormalities; *Gastroesophageal-Reflux-complications; *Mental-Retardation-complications
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE
AN: 92225534
UD: 9207
MEDLINE EXPRESS (R) 1990-1994 105 of 144
TI: Aicardi syndrome. A clinicopathologic case report including electron microscopic observations.
AU: Font-RL; Marines-HM; Cartwright-J Jr; Bauserman-SC
AD: Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston 77030.
SO: Ophthalmology. 1991 Nov; 98(11): 1727-31
ISSN: 0161-6420
PY: 1991
LA: ENGLISH
CP: UNITED-STATES
AB: Aicardi syndrome is characterized by infantile spasms, agenesis of the corpus callosum, severe mental retardation, and a characteristic chorioretinopathy with lacunar defects. The authors report on a 2-year-old girl with congenital hydrocephaly who was found unresponsive by the baby-sitter and died shortly thereafter. At autopsy, the histopathologic findings, which were confined to the brain and eyes, were found highly characteristic of AIC. The main abnormalities included agenesis of the corpus callosum, micropolygyria, bilateral papillomas of choroid plexi, bilateral microphthalmia, bilateral hypoplasia of the optic nerves, bilateral colobomas of the juxtapapillaris choroid and optic disc, bilateral total retinal detachment with dysplastic rosettes and chorioretinal lacunae with focal thinning, and atrophy of the retinal pigment epithelium and choroid. A detailed histopathologic study of the ocular findings and the brain anomalies is presented. The results of scanning electron microscopy of the chorioretinal lacunae demonstrated peculiar papillary proliferations of the retinal pigment epithelium in both eyes.
MESH: Child,-Preschool; Coloboma-pathology; Corpus-Callosum-pathology; Hydrocephalus-pathology; Optic-Nerve-abnormalities; Optic-Nerve-pathology; Pigment-Epithelium-of-Eye-ultrastructure; Syndrome-
MESH: *Choroid-Diseases-pathology; *Corpus-Callosum-abnormalities; *Retinal-Diseases-pathology; *Spasms,-Infantile-pathology
TG: Case-Report; Female; Human; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 92195588
UD: 9206
MEDLINE EXPRESS (R) 1990-1994 106 of 144
TI: Weak or missing paw lateralization in a mouse strain (I/LnJ) with congenital absence of the corpus callosum.
AU: Gruber-D; Waanders-R; Collins-RL; Wolfer-DP; Lipp-HP
AD: Institute of Anatomy, University of Zurich, Switzerland.
SO: Behav-Brain-Res. 1991 Dec 13; 46(1): 9-16
ISSN: 0166-4328
PY: 1991
LA: ENGLISH
CP: NETHERLANDS
AB: Ward et al. (Brain Research 424 (1987) 84-88) have reported that reduced size of the corpus callosum (CC) was associated with a lower degree of paw preference in the mouse strain 129/J but not in the strain BALB/cCF. Both strains show individually different degrees of development of the CC but mice completely lacking CC occur rarely. The mouse strain I/LnJ shows complete agenesis of the CC. Thus, we have compared the degree of paw lateralization by means of a food reaching task in two samples of I/LnJ mice (n1 = 81, n2 = 93) with that of two common mouse strains which show a normal CC (C57BL/6JIbm, n = 44; DBA/2JZur, n = 48). The two samples of I/LnJ mice were tested in different laboratories. The first sample of I/LnJ mice had a mean age of 36 weeks. As compared to the control mice, the males but not the females showed a significantly reduced degree of paw preference. Both, callosal and acallosal mice showed a preference for left choices. The replication sample of I/LnJ mice contained only animals between 6 and 8 weeks old. All of them were ambilateral. There was no side preference and no gender difference. We conclude that congenital absence of the CC is a factor which may substantially interfere with the development of paw lateralization. However, depending on age and gender, about half of the acallosal mice develop a paw preference.
MESH: Behavior,-Animal-physiology; Brain-pathology; Corpus-Callosum-pathology; Foot-physiology; Mice-; Mice,-Inbred-BALB-C; Mice,-Inbred-DBA; Mice,-Neurologic-Mutants
MESH: *Corpus-Callosum-abnormalities; *Laterality-physiology
TG: Animal; Female; Male; Support,-Non-U.S.-Gov't; Support,-U.S.-Gov't,-P.H.S.
PT: JOURNAL-ARTICLE
CN: GM23618GMNIGMS
AN: 92153320
UD: 9205
MEDLINE EXPRESS (R) 1990-1994 107 of 144
TI: The MR equivalents of cerebral hemispheric disconnection: a telencephalic commissuropathy.
AU: Jinkins-JR
AD: Department of Radiology, University of Texas Health Science Center, San Antonio 78284-7800.
SO: Comput-Med-Imaging-Graph. 1991 Sep-Oct; 15(5): 323-31
ISSN: 0895-6111
PY: 1991
LA: ENGLISH
CP: UNITED-STATES
AB: Since the original observations of cerebral disconnection in experimental conditions with animal models, the surgical division of the cerebral commissures for control of seizure activity has led to the description of a human hemispheric disconnection syndrome. More recently, MR has revealed a spectrum of conditions of the forebrain responsible for the natural development and acquired occurrence of this unique commissural syndrome. Acutely, nonspecific expressions of disconnection may be observed; however, there are no explicit behavioral manifestations of this syndrome in the chronic state. The signs of stabilized hemispheric disconnection are only elicitable via sophisticated, neuropsychological testing performed by experienced technicians. Included in the present series of callosal pathology were individuals with agenesis, surgical section, infarction, trauma, glioma, and Marchiafava-Bignami disease. On specialized examination, the surgical "split-brain" patients illustrated the classic syndrome of a halt of interhemispheric transfer of information, a block of nondominant hemisphere access to language functions and an inhibition of dominant hemisphere access to superior visuospatial capacity. The nonsurgical subjects with developmental callosal agenesis and acquired pathologic processes involving the callosum revealed a varied, nonspecific reduction in cognitive function most probably related to associated extracallosal hemispheric pathology. No external abnormalities in behavior which could be attributed specifically to the callosal findings were identified chronically, although some progressive diseases suggested the presence of a subacute symptomatic phase of the disconnection syndrome. Any condition which causes the division, destructive insult, or primary ontogenic nondecussation of commissural axons will produce an interference in interhemispheric, interneuronal communication. This is manifested by individual degrees of covert interhemispheric data transfer arrest and of reduced bidirectional dominant-nondominant hemispheric access and telencephalic integrative capacity, consistent with a cerebral commissuropathy. This study reveals the MR equivalents of the hemispheric disconnection syndrome which occur in many nonspecific pathologic conditions of the cerebrum, but which result in few if any overt behavioral aberrations in the stabilized state.
MESH: Adult-; Aged-; Brain-Neoplasms-diagnosis; Cerebral-Infarction-diagnosis; Child,-Preschool; Corpus-Callosum-pathology; Epilepsy-surgery; Glioma-diagnosis; Middle-Age; Postoperative-Complications-diagnosis
MESH: *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Dominance,-Cerebral-physiology; *Magnetic-Resonance-Imaging
TG: Female; Human; Male
PT: JOURNAL-ARTICLE
AN: 92097012
UD: 9204
MEDLINE EXPRESS (R) 1990-1994 108 of 144
TI: [Corpus callosum agenesis. Interhemispheric integration of semantic information]
TO: Corpus-callosum-Agenesie. Interhemispharische Integration semantischer Information.
AU: Munte-TF; Heinze-HJ
AD: Neurologische Klinik, Medizinische Hochschule Hannover.
SO: Nervenarzt. 1991 Oct; 62(10): 629-36
ISSN: 0028-2804
PY: 1991
LA: GERMAN; NON-ENGLISH
CP: GERMANY
MESH: Adult-; Brain-Mapping; Evoked-Potentials,-Visual-physiology; Magnetic-Resonance-Imaging; Middle-Age
MESH: *Attention-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-physiopathology; *Dominance,-Cerebral-physiology; *Reading-; *Semantics-
TG: Case-Report; Female; Human; Male
PT: JOURNAL-ARTICLE
AN: 92086081
UD: 9203
MEDLINE EXPRESS (R) 1990-1994 109 of 144
TI: Absence of disconnexion syndrome in callosal agenesis and early callosotomy: brain reorganization or lack of structural specificity during ontogeny?
AU: Lassonde-M; Sauerwein-H; Chicoine-AJ; Geoffroy-G
AD: Groupe de Recherche en Neuropsychologie Experimentale, Universite de Montreal, Canada.
SO: Neuropsychologia. 1991; 29(6): 481-95
ISSN: 0028-3932
PY: 1991
LA: ENGLISH
CP: ENGLAND
AB: Four acallosal subjects, one child, aged 5, and three adults, as well as five epileptic patients who underwent callosotomy between the ages of 6-21 years, were tested on a variety of intra- and intermanual tasks in a study aimed at elucidating the developmental aspects of callosal plasticity. The performance of the clinical sample was compared to that of 48 normal children, aged 5-12 years, an age span generally considered to coincide with the final stages of callosal maturation. As previously reported, interhemispheric integration improved with increasing age in the normal sample. The two patients having undergone callosotomy in childhood performed as well as their normal peers, whereas the three others who had the operation in late adolescence or adulthood showed the typical disconnexion deficits reported in the literature. The acallosal subjects, including the youngest one, outperformed all groups. We speculate that the remarkable plasticity seen in the acallosals and the young callosotomized patients may be related to a critical period in development coinciding with a phase of synaptic overproduction and redundancy that would favor the reinforcement of alternative neural pathways. The compensatory mechanisms appear to become more limited in late adolescence when synaptic distribution presumably assumes adult patterns.
MESH: Adolescence-; Adult-; Attention-physiology; Brain-Mapping; Child-; Child,-Preschool; Corpus-Callosum-physiopathology; Epilepsy-physiopathology; Follow-Up-Studies; Laterality-physiology; Neuropsychological-Tests; Postoperative-Complications-physiopathology; Stereognosis-physiology
MESH: *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Dominance,-Cerebral-physiology; *Epilepsy-surgery; *Nerve-Regeneration-physiology; *Neuronal-Plasticity-physiology
TG: Female; Human; Male; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 92050164
UD: 9202
MEDLINE EXPRESS (R) 1990-1994 110 of 144
TI: [Study of cerebral circulation and cerebrospinal fluid dynamics in a patient with agenesis of the corpus callosum using 123I-IMP SPECT and cine-mode MRI]
AU: Umahara-T; Arai-H; Hanyu-H; Yamaguchi-K; Iwamoto-T
AD: Department of Geriatric Medicine, Tokyo Medical College.
SO: Rinsho-Shinkeigaku. 1991 Apr; 31(4): 465-7
ISSN: 0009-918X
PY: 1991
LA: JAPANESE; NON-ENGLISH
CP: JAPAN
AB: A right-handed, 77-year-old man, complaining of dizziness, was diagnosed as agenesis of the corpus callosum (ACC) by MRI, which demonstrated a complete defect of the corpus callosum (CC) with symmetrical enlargement of the posterior horns of the bilateral ventricles (colpocephy) and focal hypo-plasticity of the frontal lobes. Neurological examination revealed only mild impairment of mental function and poor transfer of tactile form-board learning from the right hand to the left hand. As to the cerebral circulation detected by 123I-IMP SPECT, isotope distribution corresponded to the MRI brain images, though the defects were clearly seen on the medial surfaces of the bilateral frontal lobes, so interhemispheric fissure seemed to be opened widely. IV-DSA revealed hypo-vascularity in the anterior territory of the anterior cerebral arteries. These findings suggested that this localized defect was due to hypo-vascularity and focal hypo-plasticity of the frontal lobes. On the other hand, cine-mode MRI findings that no signal-void phenomenon was found between the third ventricle and the longitudinal fissure indicated no shunt in cerebrospinal fluid.
MESH: Aged-; Cerebrospinal-Fluid-physiology; English-Abstract
MESH: *Cerebrovascular-Circulation; *Corpus-Callosum-abnormalities; *Magnetic-Resonance-Imaging; *Tomography,-Emission-Computed,-Single-Photon
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE
AN: 92006394
UD: 9201
MEDLINE EXPRESS (R) 1990-1994 111 of 144
TI: Osteochondrodysplasia with rhizomelia, platyspondyly, callosal agenesis, thrombocytopenia, hydrocephalus, and hypertension.
AU: Faye-Petersen-OM; Ward-K; Carey-JC; Knisely-AS
AD: Department of Pathology, Primary Children's Medical Center, University of Utah School of Medicine, Salt Lake City.
SO: Am-J-Med-Genet. 1991 Aug 1; 40(2): 183-7
ISSN: 0148-7299
PY: 1991
LA: ENGLISH
CP: UNITED-STATES
AB: A female infant born at term to phenotypically normal nonconsanguinous parents had hypertension, thrombocytopenia, hydrocephalus, callosal agenesis, and nonlethal rhizomelic osteochondrodysplasia. Her osteochondrodysplasia was characterized roentgenographically by shortening and metaphyseal broadening of long bones, without bowing, and by platyspondyly, with deficient ossification of dorsal and central portions of vertebral bodies. By light microscopy, the iliac crest growth plate showed expansion of the zone of chondrocyte hypertrophy and degeneration, with faulty columnar alignment, sparse vascular ingrowth, and irregular mineralization at the zone of chondroosseous transformation. These findings appear to define a novel osteochondrodysplasia, which in association with hypertension, thrombocytopenia, hydrocephalus, and callosal agenesis may constitute a new syndrome.
MESH: Infant,-Newborn; Osteochondrodysplasias-radiography; Syndrome-
MESH: *Corpus-Callosum-abnormalities; *Hydrocephalus-; *Hypertension-; *Osteochondrodysplasias-; *Spine-abnormalities; *Thrombocytopenia-
TG: Case-Report; Female; Human; Support,-U.S.-Gov't,-P.H.S.
PT: JOURNAL-ARTICLE
CN: 5T32DK07115DKNIDDK
AN: 91377805
UD: 9112
MEDLINE EXPRESS (R) 1990-1994 112 of 144
TI: Acrocallosal syndrome: a new case.
AU: Lungarotti-MS; Marinelli-D; Mezzetti-D; Caputo-N; Calabro-A
AD: Istituto di Pediatria, Universita di Perugia, Italy.
SO: Am-J-Med-Genet. 1991 Jul 1; 40(1): 94-6
ISSN: 0148-7299
PY: 1991
LA: ENGLISH
CP: UNITED-STATES
AB: We describe a 2-month-old infant girl with typical clinical manifestations of the acrocallosal syndrome: characteristic face, agenesis of corpus callosum, polydactyly associated with other anomalies of the extremities, and mental retardation. The importance of a correct nosology and genetic counseling is underlined on the basis of the description of familiar cases of the syndrome.
MESH: Abnormalities,-Multiple-radiography; Brain-radiography; Fingers-abnormalities; Genes,-Recessive; Infant,-Newborn; Mental-Retardation-genetics; Syndrome-; Toes-abnormalities; Tomography,-X-Ray-Computed
MESH: *Abnormalities,-Multiple-genetics; *Corpus-Callosum-abnormalities
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 91361948
UD: 9112
MEDLINE EXPRESS (R) 1990-1994 113 of 144
TI: Limitations of interhemispheric extracallosal transfer of visual information in callosal agenesis.
AU: Karnath-HO; Schumacher-M; Wallesch-CW
AD: Department of Neurology, University of Freiburg, F.R.G.
SO: Cortex. 1991 Jun; 27(2): 345-50
ISSN: 0010-9452
PY: 1991
LA: ENGLISH
CP: ITALY
AB: A 57-year-old patient with callosal but not anterior commissure agenesis was investigated with a visual interfield comparison and a naming task. Stimuli were presented tachistoscopically either bilateral-simultaneously or unilaterally in the LVF and/or RVF. The stimuli presented bilaterally differed with respect to their degree of similarity. Whereas the patient was able to detect gross differences between stimuli presented in the left and right half-field, he was impaired at discriminating similar and identical stimuli across the half-fields. Identification by naming was correct on unilateral presentation of a stimulus, while with bilateral presentation of two stimuli, errors increased considerably with the stimulus named second. The data are thought to indicate a limited capacity of the extracallosal commissures, probably the anterior, for the transfer of visual information.
MESH: Cerebellar-Diseases-diagnosis; Cerebellar-Diseases-physiopathology; Cerebellar-Diseases-psychology; Cerebral-Infarction-diagnosis; Cerebral-Infarction-physiopathology; Cerebral-Infarction-psychology; Corpus-Callosum-physiopathology; Magnetic-Resonance-Imaging; Middle-Age; Neuropsychological-Tests; Pattern-Recognition,-Visual-physiology; Recall-physiology; Tomography,-X-Ray-Computed
MESH: *Corpus-Callosum-abnormalities; *Dominance,-Cerebral-physiology
TG: Case-Report; Female; Human; Male; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 91347681
UD: 9112
MEDLINE EXPRESS (R) 1990-1994 114 of 144
TI: The effects of total and partial callosal agenesis on the development of paw preference performance in the BALB/cCF mouse.
AU: Schmidt-SL; Manhaes-AC; de-Moraes-VZ
AD: Departamento de Neurobiologia, Instituto, Universidade Federal do Rio de Janeiro, Brazil.
SO: Brain-Res. 1991 Apr 5; 545(1-2): 123-30
ISSN: 0006-8993
PY: 1991
LA: ENGLISH
CP: NETHERLANDS
AB: The relation between callosal defects and paw preference was investigated in 85 male mice of the BALB/cCF strain. Paw preference was also studied in 30 male Swiss mice. Directional laterality and magnitude of laterality devoid of directionality were evaluated independently. The study of the magnitude of paw preference showed that male BALB/cCF mice were more strongly lateralized than Swiss mice. There was no difference between BALB/cCF mice with callosal defects (abnormal group) and normal BALB/cCF mice. The analysis of directional laterality indicated a population tendency for left-paw use in BALB/cCF as compared to Swiss mice. Furthermore, the percentage of left-pawed animals in the abnormal group (78%) was significantly different from chance level, as opposed to an absence of such differences in the normal BALB/cCF and in Swiss mice. It was concluded that developmental disturbance of the corpus callosum is related to the appearance of a directional populational asymmetry in paw preference.
MESH: Corpus-Callosum-abnormalities; Forelimb-; Mice-; Mice,-Inbred-BALB-C; Mice,-Inbred-Strains; Reference-Values; Species-Specificity
MESH: *Corpus-Callosum-physiology; *Laterality-physiology
TG: Animal; Comparative-Study; Male; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 91316562
UD: 9111
MEDLINE EXPRESS (R) 1990-1994 115 of 144
TI: Miller-Dieker syndrome with ring chromosome 17.
AU: Sharief-N; Craze-J; Summers-D; Butler-L; Wood-CB
AD: Department of Child Health, Queen Elizabeth Hospital for Children, London.
SO: Arch-Dis-Child. 1991 Jun; 66(6): 710-2
ISSN: 0003-9888
PY: 1991
LA: ENGLISH
CP: ENGLAND
AB: A girl presented at 6 weeks of age with failure to thrive and arching of the back. She had various dysmorphic features, hepatosplenomegaly, and developmental delay. The electroencephalogram and cranial ultrasound were abnormal, and a computed tomogram showed lissencephaly and apparent agenesis of the corpus callosum. Because of frequent aspiration she became oxygen dependent. She later developed intractable convulsions and died at the age of 9 months.
MESH: Brain-pathology; Child-Development-Disorders-etiology; Child,-Preschool; Facial-Bones-abnormalities; Infant,-Newborn; Syndrome-; Tomography,-X-Ray-Computed
MESH: *Abnormalities,-Multiple; *Brain-abnormalities; *Chromosomes,-Human,-Pair-17; *Corpus-Callosum-abnormalities; *Ring-Chromosomes
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 91273411
UD: 9109
SB: AIM
MEDLINE EXPRESS (R) 1990-1994 116 of 144
TI: [Glio-ependymal cyst in the lateral ventricle complicated by agenesis of the corpus callosum]
AU: Niwa-J; Okuyama-T; Shimizu-K; Hirai-H
AD: Department of Nerosurgery, Hakodate Municipal Hospital.
SO: No-Shinkei-Geka. 1991 Apr; 19(4): 359-63
ISSN: 0301-2603
PY: 1991
LA: JAPANESE; NON-ENGLISH
CP: JAPAN
AB: The case is that of a 5-year-old male who was admitted to the hospital for a further examination because of the onset of seizure observed twice. He was delivered at full term by Cesarean section, and had had impairment of movement of his left hand since birth. The results of the first examination performed at the time of his admission to the hospital revealed mild neurological disturbance of the left hand. The CT scanning performed showed partial agenesis of the corpus callosum and a bicameral cyst enhancing the cystic wall extending from the right anterior horn of the lateral ventricle to the body. By MRI sagittal plane, cystic masses presented low signal intensity on the T-1 weighted image, and they showed high signal intensity on the T-2 weighted image. The coronal plane showed that the cysts extended from the midline of the ventricle to the lateral. Cystectomy was performed using the transventricular approach. Thus communication between the cyst and lateral ventricle was made possible. The cystic wall was macroscopically white and elastically soft, and contained vascular components. Histopathologically, it consisted of 3 layers of ciliated cuboidal epithelium, glia cells and connective tissue respectively. We diagnosed the condition as glio-ependymal cyst in the lateral ventricle complicated by partial agenesis of the corpus callosum.
MESH: Brain-Diseases-pathology; Brain-Diseases-surgery; Child,-Preschool; Cysts-pathology; Cysts-surgery; English-Abstract; Epithelium-pathology
MESH: *Brain-Diseases-complications; *Cerebral-Ventricles; *Corpus-Callosum-abnormalities; *Cysts-complications; *Neuroglia-pathology
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE
AN: 91261016
UD: 9109
MEDLINE EXPRESS (R) 1990-1994 117 of 144
TI: Partial agenesis of the anterior corpus callosum: correlation between appearance, imaging, and neuropathology.
AU: Schaefer-GB; Shuman-RM; Wilson-DA; Saleeb-S; Domek-DB; Johnson-SF; Bodensteiner-JB
AD: Department of Pediatrics, University of Nebraska Medical Center, Omaha 68198-5440.
SO: Pediatr-Neurol. 1991 Jan-Feb; 7(1): 39-44
ISSN: 0887-8994
PY: 1991
LA: ENGLISH
CP: UNITED-STATES
AB: Two patients with partial (semilobar) holotelencephaly are reported with apparent partial agenesis of the corpora callosa. These patients are of interest because they appear to possess the posterior portion of the corpus callosum but not its anterior component. Because the corpus callosum develops in the commissural plate rostrally and is elaborated in a rostral-caudal gradient, this apparent lack of the rostral component is embryologically puzzling. The neuropathologic studies of 1 patient resolved the apparent discrepancy between magnetic resonance imaging and embryology of the corpus callosum. With these data, we addressed the embryologic factors that may explain this malformation.
MESH: Abnormalities,-Multiple-pathology; Child,-Preschool; Corpus-Callosum-pathology; Follow-Up-Studies; Infant-; Infant,-Newborn; Mental-Retardation-diagnosis; Mental-Retardation-pathology
MESH: *Abnormalities,-Multiple-diagnosis; *Corpus-Callosum-abnormalities; *Magnetic-Resonance-Imaging; *Tomography,-X-Ray-Computed
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 91229600
UD: 9108
MEDLINE EXPRESS (R) 1990-1994 118 of 144
TI: Stereo perception in callosal agenesis and partial callosotomy.
AU: Jeeves-MA
AD: Psychological Laboratory, University of St Andrews, Fife, Scotland, U.K.
SO: Neuropsychologia. 1991; 29(1): 19-34
ISSN: 0028-3932
PY: 1991
LA: ENGLISH
CP: ENGLAND
AB: Stereoperception in two acallosal patients and two partial callosotomy patients was compared with that of three normal subjects. All three patients with the splenium missing, whether due to agenesis or surgical intervention, showed midline deficits and broadly similar profiles; namely, they made few uncrossed midline responses. The patient with partial callosal section but with the splenium almost totally spared performed better at the midline than in the periphery. All degrees of disconnection produced some overall loss of performance, confirming the results of Hamilton and Vermeire (In Two Hemispheres--One Brain, F. Lepore, M. Pitto and H. H. Jasper (Editors), pp. 315-333. Alan R. Liss Inc., New York, 1986) and Hamilton et al. (Suppl. Invest. Ophthal. Vis. Sci. 28, 294, 1987). The results are discussed in the context of earlier reports of human and animal studies of stereoperception. Bearing in mind reports of structural alterations in layer III of the striate cortex in acallosals (Shoumjra, K. et al. Brain Res. 93, 241-252, 1975. Also, Akert, K. et al. Trans. Am. Neurol. Assoc. 79, 151-153, 1954), it is speculated that the specific difficulties encountered by them in handling uncrossed disparities may be due to a marked reduction or absence of far neurones in acallosal brains (Poggio, G. F. and Poggio, T. Ann. Rev. Neurosci. 7, 379-412, 1984). The likely importance of the anterior commissure in the efficient integration of crossed disparity (near neurones) (Cowey, A. In Brain Mechanisms and Spatial Vision, D. Ingle (Editor), NATO Advanced Study Institute Series, Martinus Nijhoff, The Hague, 1985) is seen as a possible explanation of the acallosals relative success in making crossed disparity judgements. The variability of performance in normals documented by Hamilton and Vermeire (In Two Hemispheres--One Brain, F. Lepore, M. Pitto and H. H. Jasper (Editors), pp. 315-333. Alan R. Liss Inc., New York, 1986) and Hamilton et al. (Suppl. Invest. Ophthal. Vis. Sci. 28, 294, 1987) is, not surprisingly, even more marked amongst acallosals.
MESH: Adult-; Corpus-Callosum-abnormalities; Corpus-Callosum-surgery; Discrimination-Learning-physiology; Neurons-physiology; Orientation-physiology; Postoperative-Complications-physiopathology
MESH: *Corpus-Callosum-physiopathology; *Depth-Perception-physiology; *Dominance,-Cerebral-physiology
TG: Human; Male; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 91204140
UD: 9107
MEDLINE EXPRESS (R) 1990-1994 119 of 144
TI: Polyasplenia, caudal deficiency, and agenesis of the corpus callosum.
AU: Rodriguez-JI; Palacios-J; Omenaca-F; Lorente-M
AD: Departamento de Anatomia Patologica, Hospital La Paz, Madrid, Spain.
SO: Am-J-Med-Genet. 1991 Jan; 38(1): 99-102
ISSN: 0148-7299
PY: 1991
LA: ENGLISH
CP: UNITED-STATES
AB: Fullana et al. [Am J Med Genet (suppl. 2): 23-29, 1986] reported on 2 sibs with an autosomal recessive syndrome of caudal deficiency and polyasplenia anomalies. We report on a similar patient in which agenesis of the corpus callosum (ACC) was also found. Such an association has not been reported previously. This finding of ACC is to be interpreted as another midline anomaly rather than as a causally independent malformation.
MESH: Infant-; Spleen-abnormalities
MESH: *Corpus-Callosum-abnormalities; *Spine-abnormalities
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 91189255
UD: 9107
MEDLINE EXPRESS (R) 1990-1994 120 of 144
TI: [A case of Aicardi syndrome with moderate psychomotor retardation]
AU: Abe-K; Mitsudome-A; Ogata-H; Ohfu-M; Takakusaki-M
AD: Department of Neuro-Pediatrics, Simonoseki Welfare Hospital.
SO: No-To-Hattatsu. 1990 Jul; 22(4): 376-80
ISSN: 0029-0831
PY: 1990
LA: JAPANESE; NON-ENGLISH
CP: JAPAN
AB: A five-year-old girl of Aicardi syndrome showed moderate psychomotor retardation. She could walk and communicate. At six months of age, she developed salaam convulsion with series. Convulsions disappeared immediately after ACTH treatment. At eighteen months of age, she developed myoclonic seizures. From three years of age, head-nodding seizures with series relapsed and could not be controlled. But she could walk alone at two years old and speak a word at one and half years old. A degree of her psychomotor retardation was more slightly than others published cases of Aicardi syndrome. There were eleven reports, included our case, with mild retardation in Aicardi syndrome. The features of these are 1) late onset of seizures, 2) good response to ACTH therapy, 3) no significant abnormalities of brain except for agenesis of corpus callosum.
MESH: Child,-Preschool; Choroid-Diseases-pathology; English-Abstract; Mental-Retardation; Psychomotor-Disorders-drug-therapy; Psychomotor-Disorders-pathology; Retinal-Diseases-pathology; Syndrome-
MESH: *Corpus-Callosum-abnormalities; *Corticotropin-therapeutic-use; *Psychomotor-Disorders-physiopathology; *Seizures-drug-therapy
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
RN: 9002-60-2
NM: Corticotropin
AN: 90380449
UD: 9012
MEDLINE EXPRESS (R) 1990-1994 121 of 144
TI: [Asphyxiating thoracic dysplasia associated with hepatic ductal hypoplasia, agenesis of the corpus callosum and Dandy-Walker syndrome]
TO: Dystrophie thoracique asphyxiante de Jeune associee a une hypoplasie ductulaire hepatique, une agenesie du corps calleux et un syndrome de Dandy-Walker.
AU: Trabelsi-M; Hammou-Jeddi-A; Kammoun-A; Bennaceur-B; Gharbi-HA
AD: Service de pediatrie, hopital d'enfants de Tunis, Tunisie.
SO: Pediatrie-Bucur. 1990; 45(1): 35-8
ISSN: 0031-4021
PY: 1990
LA: FRENCH; NON-ENGLISH
CP: FRANCE
AB: The authors report on a case of a newborn with asphyxiating thoracic dysplasia who died 36 h after birth. This chondrodysplasia was associated with hepatic ductular hypoplasia, agenesis of the corpus callosum and Dandy-Walker malformation. To our knowledge, such an association has not previously been reported in the literature.
MESH: English-Abstract; Infant,-Newborn
MESH: *Bile-Ducts,-Intrahepatic-abnormalities; *Cholestasis,-Intrahepatic-complications; *Corpus-Callosum-abnormalities; *Dandy-Walker-Syndrome-complications; *Ellis-Van-Creveld-Syndrome-complications; *Hydrocephalus-complications; *Thorax-abnormalities
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE; REVIEW; REVIEW,-TUTORIAL
AN: 90221681
UD: 9007
MEDLINE EXPRESS (R) 1990-1994 122 of 144
TI: Agenesis and lipoma of the corpus callosum: MR findings [letter]
AU: Hua-CL
SO: AJR-Am-J-Roentgenol. 1990 Jun; 154(6): 1348
ISSN: 0361-803X
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
MESH: Child,-Preschool
MESH: *Brain-Neoplasms-diagnosis; *Corpus-Callosum-abnormalities; *Lipoma-diagnosis; *Magnetic-Resonance-Imaging
TG: Case-Report; Female; Human
PT: LETTER
AN: 90247274
UD: 9008
SB: AIM
MEDLINE EXPRESS (R) 1990-1994 123 of 144
TI: Apparent atypical callosal dysgenesis: analysis of MR findings in six cases and their relationship to holoprosencephaly.
AU: Barkovich-AJ
AD: Department of Radiology, University of California, San Francisco 94043.
SO: AJNR-Am-J-Neuroradiol. 1990 Mar-Apr; 11(2): 333-9
ISSN: 0195-6108
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
AB: The MR scans of six pediatric patients with apparent atypical callosal dysgenesis (presence of the dorsal corpus callosum in the absence of a rostral corpus callosum) were critically analyzed and correlated with developmental information in order to assess the anatomic, embryologic, and developmental implications of this unusual anomaly. Four patients had semilobar holoprosencephaly; the dorsal interhemispheric commissure in these four infants resembled a true callosal splenium. All patients in this group had severe developmental delay. The other two patients had complete callosal agenesis with an enlarged hippocampal commissure mimicking a callosal splenium; both were developmentally and neurologically normal. The embryologic implications of the presence of these atypical interhemispheric connections are discussed. Differentiation between semilobar holoprosencephaly and agenesis of the corpus callosum with enlarged hippocampal commissure--two types of apparent atypical callosal dysgenesis--can be made by obtaining coronal, short TR/TE MR images through the frontal lobes. Such differentiation has critical prognostic implications.
MESH: Brain-embryology; Child-; Child-Development-Disorders-etiology; Child,-Preschool; Infant-; Infant,-Newborn
MESH: *Abnormalities,-Multiple-diagnosis; *Brain-abnormalities; *Corpus-Callosum-abnormalities; *Magnetic-Resonance-Imaging
TG: Female; Human; Male
PT: JOURNAL-ARTICLE
AN: 90195852
UD: 9006
MEDLINE EXPRESS (R) 1990-1994 124 of 144
TI: Multi-institutional survey of the Aicardi syndrome in Japan.
AU: Yamagata-T; Momoi-M; Miyamoto-S; Kobayashi-S; Kamoshita-S
AD: Department of Pediatrics, Jichi Medical School, Tochigi, Japan.
SO: Brain-Dev. 1990; 12(6): 760-5
ISSN: 0387-7604
PY: 1990
LA: ENGLISH
CP: JAPAN
AB: The first multi-institutional survey of the Aicardi syndrome in Japan was performed during 1985 and 1986. Among the 20 collected cases, 9 fulfilled the typical clinical triad; infantile spasms, agenesis of the corpus callosum and chorioretinal lacuna. Three cases had agenesis of corpus callosum and chorioretinal lacuna. Five cases had agenesis of the corpus callosum and infantile spasms. We classified 12 cases with both agenesis of the corpus callosum and a lacuna as typical cases, and the remaining 8 cases as atypical cases. No familial cases were found among either the typical or atypical cases. The presence of the vertebral anomalies or other anomalies in the atypical cases, which were frequently observed in the typical cases, suggested that unknown common processes were affected in both the typical and atypical groups.
MESH: Child-; Child,-Preschool; Infant-; Japan-; Maternal-Age; Paternal-Age; Syndrome-
MESH: *Choroid-abnormalities; *Corpus-Callosum-abnormalities; *Retina-abnormalities; *Spasms,-Infantile-epidemiology
TG: Female; Human; Male; Support,-Non-U.S.-Gov't
PT: CLINICAL-TRIAL; JOURNAL-ARTICLE; MULTICENTER-STUDY
AN: 91229199
UD: 9108
MEDLINE EXPRESS (R) 1990-1994 125 of 144
TI: Corpus callosum agenesis, spastic quadriparesis and irregular lining of the lateral ventricles on CT-scan. A distinct X-linked mental retardation syndrome?
AU: Vles-JS; Fryns-JP; Folmer-K; Boon-P; Buttiens-M; Grubben-C; Janevski-B
AD: Department of Child Neurology, University of Maastricht, The Netherlands.
SO: Genet-Couns. 1990; 1(2): 97-102
ISSN: 1015-8146
PY: 1990
LA: ENGLISH
CP: SWITZERLAND
AB: This report gives a description of 4 male patients, two of whom are sibs, two of whom are uncle and cousin. They appear to have psychomotor retardation, spastic quadriparesis and on CT (partial) agencies of the corpus callosum, and irregular lining of the lateral ventricles, without craniofacial abnormalities or seizures. Although the mode of inheritance of agenesis of the corpus callosum is still difficult to establish, in these 4 male patients an X-linked recessive inheritance is the most likely mode. A review of the literature with concern to the heredity of agenesis of the corpus callosum is presented. The clinical and neurological findings in the present four male patients allow for the delineation of a new X-linked mental retardation syndrome.
MESH: Adult-; Corpus-Callosum-radiography; Genes,-Recessive-genetics; Mental-Retardation-radiography; Middle-Age; Sex-Chromosome-Abnormalities-radiography; Syndrome-
MESH: *Cerebral-Ventricles-abnormalities; *Cerebral-Ventriculography; *Corpus-Callosum-abnormalities; *Linkage-Genetics-genetics; *Mental-Retardation-genetics; *Quadriplegia-genetics; *Sex-Chromosome-Abnormalities-genetics; *Spastic-Paraplegia,-Hereditary-genetics; *Tomography,-X-Ray-Computed; *X-Chromosome
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE; REVIEW; REVIEW,-TUTORIAL
AN: 91182300
UD: 9107
MEDLINE EXPRESS (R) 1990-1994 126 of 144
TI: Prenatal echographic diagnosis of corpus callosum agenesis. The Nancy experience 1982-1989.
AU: Blum-A; Andre-M; Droulle-P; Husson-S; Leheup-B
AD: Departement de Radiologie Echographie, Laboratoire de biologie Sexuelle, Nancy, France.
SO: Genet-Couns. 1990; 1(2): 115-26
ISSN: 1015-8146
PY: 1990
LA: ENGLISH
CP: SWITZERLAND
AB: In this report we present the Nancy experience on the prenatal echographic diagnosis of corpus callosum agenesis in a consecutive series of 17 patients. The pitfalls and difficulties in the prenatal echographic diagnosis of ACC is emphasized. They are related with the particular development of the corpus callosum and the limitations of diagnostic procedures. Moreover, the variability of corpus callosum anomalies is illustrated, and the difficulties in establishing long term prognosis in the individual patient documented.
MESH: Abnormalities,-Multiple-genetics; Abnormalities,-Multiple-ultrasonography; Cerebral-Ventricles-abnormalities; Cerebral-Ventricles-ultrasonography; Corpus-Callosum-ultrasonography; Fetal-Growth-Retardation-genetics; Fetal-Growth-Retardation-ultrasonography; Follow-Up-Studies; France-; Infant,-Newborn; Pregnancy-; Skull-abnormalities; Skull-ultrasonography
MESH: *Corpus-Callosum-abnormalities; *Ultrasonography,-Prenatal
TG: Female; Human; Male
PT: JOURNAL-ARTICLE
AN: 91182291
UD: 9107
MEDLINE EXPRESS (R) 1990-1994 127 of 144
TI: [A case of hypopituitarism associated with empty sella and agenesis of corpus callosum, a variant form of septo-optic-pituitary dysplasia]
AU: Fukutomi-T; Masakado-M; Takayanagi-R; Ohnaka-K; Sekiya-K; Haji-M; Ohasi-M; Nawata-H
AD: Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka.
SO: Fukuoka-Igaku-Zasshi. 1990 Dec; 81(12): 396-401
ISSN: 0016-254X
PY: 1990
LA: JAPANESE; NON-ENGLISH
CP: JAPAN
AB: A 41-year-old man was referred to Kyushu University Hospital for evaluation of hypothyroidism and hypocortisolemia. Pituitary function test revealed the deficiency of GH(growth hormone), ACTH(adrenocorticotropic hormone), prolactin and TSH(thyroid stimulating hormone). MRI showed empty sella and agenesis of corpus callosum. Clinical diagnosis was hypopituitarism with midline brain anomaly. Septo-optic-pituitary dysplasia (SOPD) is a syndrome characterized by agenesis of septum pellucidum or corpus callosum, optic nerve hypoplasia and congenital hypothalamic-pituitary insufficiency. Our case had no ocular anomalies, but today it is regarded as a variant form of SOPD. Evaluation of the integrity of midline brain structures in patients with congenital hypopituitarism is thus thought to be important for their etiology.
MESH: Adult-; English-Abstract; Syndrome-
MESH: *Corpus-Callosum-abnormalities; *Empty-Sella-Syndrome; *Hypopituitarism-
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE
AN: 91169357
UD: 9106
MEDLINE EXPRESS (R) 1990-1994 128 of 144
TI: Magnetic resonance imaging in the malformative syndromes with mental retardation.
AU: Gabrielli-O; Salvolini-U; Coppa-GV; Catassi-C; Rossi-R; Manca-A; Lanza-R; Giorgi-PL
AD: Department of Pediatrics, University of Ancona, Italy.
SO: Pediatr-Radiol. 1990; 21(1): 16-9
ISSN: 0301-0449
PY: 1990
LA: ENGLISH
CP: GERMANY
AB: We reported on thirteen children affected with malformative syndromes associated with mental retardation. MRI examination showed in all of them different types of anomalies; agenesis of corpus callosum, ventricular dilatation and cerebral matter alterations were the most frequent findings. The authors give a brief description of the clinical reports and of the anomalies observed with MRI; they conclude that MRI seems to be a valuable tool especially for the study of the alterations of the cerebral matter and their correlation with mental retardation.
MESH: Abnormalities,-Multiple-pathology; Acrocephalosyndactylia-pathology; Adolescence-; Arnold-Chiari-Deformity-pathology; Brain-pathology; Cerebral-Ventricles-pathology; Child-; Child,-Preschool; Corpus-Callosum-abnormalities; Corpus-Callosum-pathology; Dilatation,-Pathologic; Fetal-Alcohol-Syndrome-pathology; Gigantism-pathology; Infant-; Neuropathies,-Hereditary-Motor-and-Sensory-pathology; Noonan-Syndrome-pathology; Oculocerebrorenal-Syndrome-pathology; Syndrome-
MESH: *Abnormalities,-Multiple; *Brain-abnormalities; *Magnetic-Resonance-Imaging; *Mental-Retardation-pathology
TG: Case-Report; Human
PT: JOURNAL-ARTICLE
AN: 91141892
UD: 9105
MEDLINE EXPRESS (R) 1990-1994 129 of 144
TI: Agenesis of the corpus callosum and colloid cyst of the third ventricle: magnetic resonance imaging of an unusual association [see comments]
CM: Comment in: Can Assoc Radiol J 1991 Aug;42(4):297
AU: del-Carpio-O'Donovan-R; Cardinal-E
AD: Department of Radiology, Montreal Neurological Hospital.
SO: Can-Assoc-Radiol-J. 1990 Dec; 41(6): 375-9
ISSN: 0008-2902
PY: 1990
LA: ENGLISH
CP: CANADA
AB: Agenesis of the corpus callosum is usually associated with brain malformations or with anomalies outside the central nervous system. A colloid cyst of the third ventricle may give rise to hydrocephalus and even sudden death. The authors report the case of a 23-year-old man in whom both these uncommon conditions coexisted. The findings on computed tomography and magnetic resonance imaging are described. The colloid cyst was completely excised through a frontal craniotomy and the patient made a smooth recovery.
MESH: Adult-; Brain-Diseases-pathology; Cerebral-Ventriculography; Colloids-; Corpus-Callosum-pathology; Corpus-Callosum-radiography; Cysts-pathology; Tomography,-X-Ray-Computed
MESH: *Brain-Diseases-radiography; *Cerebral-Ventricles-pathology; *Corpus-Callosum-abnormalities; *Cysts-radiography; *Magnetic-Resonance-Imaging
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE
RN: 0
NM: Colloids
AN: 91077779
UD: 9104
MEDLINE EXPRESS (R) 1990-1994 130 of 144
TI: Ullrich-Turner syndrome with agenesis of the corpus callosum.
AU: Kimura-M; Nakajima-M; Yoshino-K
AD: Department of Pediatrics, National Sanatorium Nishi-Tottori Hospital, Japan.
SO: Am-J-Med-Genet. 1990 Oct; 37(2): 227-8
ISSN: 0148-7299
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
AB: We report on a 19-year-old woman with 45,X Ullrich-Turner syndrome who was severely mentally retarded and had hypotonia. Computer tomography (CT) scan showed agenesis of the corpus callosum. There have been few reports of gross developmental central nervous system (CNS) abnormalities in Ullrich-Turner syndrome. Only one case of Ullrich-Turner syndrome with agenesis of the corpus callosum has been reported. The high prenatal lethality of Ullrich-Turner syndrome may mask a CNS abnormality.
MESH: Adult-
MESH: *Abnormalities,-Multiple; *Corpus-Callosum-abnormalities; *Mental-Retardation; *Noonan-Syndrome
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 91063469
UD: 9103
MEDLINE EXPRESS (R) 1990-1994 131 of 144
TI: [Frontonasal dysplasia. Case report and review of the literature]
TO: Die Frontonasale Dysplasie. Falldemonstration und Literaturubersicht.
AU: Lorenz-P; Prager-B; Tellkamp-H
AD: Abteilung fur Klinische Genetik, Medizinischen Akademie, Carl Gustav Carus Dresden.
SO: Kinderarztl-Prax. 1990 Aug; 58(8): 415-20
ISSN: 0023-1495
PY: 1990
LA: GERMAN; NON-ENGLISH
CP: GERMANY
AB: FND is a non-uniform malformation complex with symptoms ranging between severe hypertelorism with bidfid nose and cranium bidfidum occultum with agenesis of the corpus callosum. Etiology and pathogenesis are discussed on the basis of a case history and some hints regarding differential diagnosis and genetic counselling are given. The exclusively sporadic occurrence of FND tells against a hereditary pathomechanism. Consequently, there is no recurrence risk. However, in families with an affected child, malformations generally tend to occur a little more often.
MESH: Abnormalities,-Multiple-genetics; Cerebral-Ventricles-abnormalities; Diagnosis,-Differential; English-Abstract; Infant,-Newborn
MESH: *Cleft-Lip-genetics; *Cleft-Palate-genetics; *Corpus-Callosum-abnormalities; *Hypertelorism-genetics; *Nose-abnormalities
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE; REVIEW; REVIEW,-TUTORIAL
AN: 91040380
UD: 9102
MEDLINE EXPRESS (R) 1990-1994 132 of 144
TI: Interhemispheric cysts in association with agenesis of the corpus callosum.
AU: Schwartz-AM; Ghatak-NR
AD: Department of Pathology, University of Rochester Medical Center, NY 14642.
SO: Clin-Neuropathol. 1990 Jul-Aug; 9(4): 177-80
ISSN: 0722-5091
PY: 1990
LA: ENGLISH
CP: GERMANY
AB: Two cases of complete agenesis of the corpus callosum each with large interhemispheric cysts are presented. The first case is an adult patient with chronic renal failure secondary to adult polycystic renal disease who was neurologically asymptomatic until she had a seizure during hemodialysis. The second case is an infant, who was diagnosed in utero as hydrocephalic, with severe mental and motor retardation and intractable seizures. The clinicopathologic findings in the two cases are presented, along with a discussion of the possible etiologies and clinical significance.
MESH: Brain-Diseases-pathology; Corpus-Callosum-pathology; Cysts-pathology; Epithelium-pathology; Infant-; Middle-Age; Seizures-etiology
MESH: *Brain-Diseases-complications; *Corpus-Callosum-abnormalities; *Cysts-complications
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 91030200
UD: 9102
MEDLINE EXPRESS (R) 1990-1994 133 of 144
TI: Reading in callosal agenesis.
AU: Temple-CM; Jeeves-MA; Vilarroya-OO
AD: Developmental Neuropsychology Unit, Royal Holloway and Bedford New College, Egham, Surrey, United Kingdom.
SO: Brain-Lang. 1990 Aug; 39(2): 235-53
ISSN: 0093-934X
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
AB: It has been suggested that deficits in explicit phonological processing are causal in developmental dyslexia. Deficits in such skills have been reported in developmental phonological dyslexia, though not in developmental surface dyslexia. The reading performance of two children with callosal agenesis, who have been previously shown to have impairments on rhyming tasks, are reported. Neither child is dyslexic in the traditional sense, since word reading levels are appropriate for age. However, both children have impaired development of the phonological reading route despite normal lexical skills. The pattern of their reading is therefore comparable to developmental phonological dyslexia. Problems in explicit phonological processing may be causal in the failure to establish an efficient phonological reading route but this is insufficient to create difficulty with word recognition itself. The corpus callosum may be essential for the normal development of a phonological reading route.
MESH: Child-; Corpus-Callosum-physiopathology; Dyslexia-physiopathology; Neuropsychological-Tests; Phonetics-; Verbal-Learning-physiology
MESH: *Corpus-Callosum-abnormalities; *Language-Development-Disorders-physiopathology; *Reading-
TG: Case-Report; Female; Human; Male; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 91028684
UD: 9102
MEDLINE EXPRESS (R) 1990-1994 134 of 144
TI: [Interhemispheric cyst of an adult associated with partial agenesis of the corpus callosum]
AU: Munemoto-S; Ishiguro-S; Kimura-A; Kuroda-E; Ueno-M; Yamamoto-S; Shimizu-H; Ueno-K
AD: Department of Neurosurgery, Ishikawa Prefectural Central Hospital.
SO: Rinsho-Hoshasen. 1990 Aug; 35(8): 959-62
ISSN: 0009-9252
PY: 1990
LA: JAPANESE; NON-ENGLISH
CP: JAPAN
AB: The authors report an adult patient with an asymptomatic interhemispheric cyst demonstrated by computerized tomography (CT), magnetic resonance imaging (MRI) scan and angiography. Partial agenesis of the corpus callosum is associated.
MESH: Adult-; Brain-Diseases-diagnosis; Cysts-diagnosis; English-Abstract
MESH: *Brain-Diseases-complications; *Corpus-Callosum-abnormalities; *Cysts-complications
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE
AN: 91013078
UD: 9101
MEDLINE EXPRESS (R) 1990-1994 135 of 144
TI: [Sacrococcygeal teratoma of newborn infants; a report of two cases]
AU: Shinoura-N; Kondo-T; Muraoka-I; Tsukamoto-Y; Yoshioka-M; Miyazawa-H
AD: Department of Neurological Surgery, National Medical Center.
SO: No-Shinkei-Geka. 1990 Jun; 18(6): 557-61
ISSN: 0301-2603
PY: 1990
LA: JAPANESE; NON-ENGLISH
CP: JAPAN
AB: Two cases of sacrococcygeal teratoma in female infants are reported. Case 1. A newborn baby with a hemispheric mass on her hip underwent surgery 3 days after birth and the lesion proved to be an immature teratoma. The serum AFP level was very high but became normal one month after the operation. The child also had agenesis of the corpus callosum and arachnoid cysts in right middle fossa. She died after developing shunt infection. Case 2. A newborn baby with a mature teratoma was operated on the day following birth. The tumor was subtotally removed, and there has been no recurrence after 6 months. Sacrococcygeal teratoma in female infants is often associated with agenesis of the corpus callosum and arachnoid cysts. They tend to develop almost at the same time as the teratoma. It is often difficult to determine whether the infant should be treated by chemotherapy or not if the teratoma is immature, especially when it has been totally removed, the serum AFP is normal, and the tumor is pathologically of a low grade.
MESH: alpha-Fetoproteins-metabolism; Arachnoid-; Corpus-Callosum-abnormalities; Cysts-complications; English-Abstract; Infant,-Newborn; Spinal-Neoplasms-blood; Spinal-Neoplasms-complications; Teratoma-blood; Teratoma-complications
MESH: *Coccyx-; *Sacrum-; *Spinal-Neoplasms-surgery; *Teratoma-surgery
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
RN: 0
NM: alpha-Fetoproteins
AN: 90370200
UD: 9012
MEDLINE EXPRESS (R) 1990-1994 136 of 144
TI: The Morning Glory syndrome associated with sphenoethmoidal encephalocele.
AU: Hope-Ross-M; Johnston-SS
AD: Department of Ophthalmology, Royal Victorial Hospital, Belfast, Northern Ireland.
SO: Ophthalmic-Paediatr-Genet. 1990 Jun; 11(2): 147-53
ISSN: 0167-6784
PY: 1990
LA: ENGLISH
CP: NETHERLANDS
AB: A 10-month-old infant was referred to the ophthalmic department of the Royal Victoria Hospital for assessment. Pregnancy and delivery had been normal. At birth, cleft lip, cleft palate, hypertelorism and a soft tissue mass in the mouth were noted. At two days of age he developed meningitis, axial computerized tomography showed a sphenoethmoidal encephalocele, and agenesis of the corpus callosum. The basal encephalocele was surgically repaired. On examination in the ophthalmic department he was able to follow a light with the left eye. He perceived light with the right eye but did not follow. There was a manifest right divergent squint, measuring -10 degrees, and a right afferent nerve defect. Examination under anaesthetic was performed. The right fundus showed a Morning Glory syndrome. The disc was pink and deeply excavated, and surrounded by a ring of chorioretinal pigmentary disturbance. There was a central tuft of glial tissue. The left fundus was normal. The association of Morning Glory syndrome and basal encephalocele is rare; four previous cases have been reported. In all patients there were associated mid-facial congenital anomalies such as cleft lip and cleft palate. The presence of a basal encephalocele should be suspected if the Morning Glory syndrome occurs in association with mid-facial congenital anomalies.
MESH: Cleft-Lip-complications; Cleft-Lip-surgery; Corpus-Callosum-abnormalities; Encephalocele-surgery; Face-abnormalities; Infant-; Syndrome-
MESH: *Abnormalities,-Multiple; *Coloboma-complications; *Encephalocele-complications; *Optic-Disk-abnormalities
TG: Case-Report; Human; Male
PT: JOURNAL-ARTICLE; REVIEW; REVIEW-OF-REPORTED-CASES
AN: 90332244
UD: 9011
MEDLINE EXPRESS (R) 1990-1994 137 of 144
TI: Prenatal diagnosis of agenesis of the corpus callosum using endovaginal ultrasound.
AU: Hilpert-PL; Kurtz-AB
AD: Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
SO: J-Ultrasound-Med. 1990 Jun; 9(6): 363-5
ISSN: 0278-4297
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
MESH: Adult-; Pregnancy-
MESH: *Abnormalities,-Multiple-diagnosis; *Corpus-Callosum-abnormalities; *Fetal-Diseases-diagnosis; *Prenatal-Diagnosis; *Ultrasonography-
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 90286027
UD: 9009
MEDLINE EXPRESS (R) 1990-1994 138 of 144
TI: Corpus callosum agenesis and uncinate seizures.
AU: Mohapatro-AK; Jain-S; Maheshwari-MC; Goulatia-RK
AD: Department of Neurology, All India Institute of Medical Sciences, New Delhi.
SO: J-Assoc-Physicians-India. 1990 May; 38(5): 371-2
ISSN: 0004-5772
PY: 1990
LA: ENGLISH
CP: INDIA
MESH: Child-
MESH: *Carbamazepine-therapeutic-use; *Corpus-Callosum-abnormalities; *Seizures-drug-therapy
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
RN: 298-46-4
NM: Carbamazepine
AN: 90354360
UD: 9011
MEDLINE EXPRESS (R) 1990-1994 139 of 144
TI: [Motor and sensory neuropathies with or without agenesis of the corpus callosum: a radiological study of 64 cases.]
TO: Neuropathie sensitivo-motrice hereditaire avec ou sans agenesie du corps calleux: etude radiologique et clinique de 64 cas.
AU: Mathieu-J; Bedard-F; Prevost-C; Langevin-P
AD: Clinique des maladies neuro-musculaires, Hopital de Chicoutimi, PQ, Canada.
SO: Can-J-Neurol-Sci. 1990 May; 17(2): 103-8
ISSN: 0317-1671
PY: 1990
LA: FRENCH; NON-ENGLISH
CP: CANADA
AB: In 1971, Andermann and Andermann described an autosomal recessive syndrome found within the Charlevoix and the Saguenay populations (Quebec, Canada) characterized by agenesis of the corpus callosum (ACC) associated with motor and sensory neuropathy, mental retardation and dysmorphic features. A study of CT in 64 patients demonstrated a total ACC in 37 cases (57.8%), partial ACC in 6 cases (9.4%) and the presence of the corpus callosum in 21 cases (32.8%). The latter was confirmed by MRI in 3 cases. CT of patients without ACC revealed a high frequency of developmental or degenerative midline anomalies, particularly interhemispheric fissure enlargement and posterior fossa atrophy. The clinical presentation and the natural course of the neuropathy, the intellectual impairment and the behavioural manifestations are identical amongst individuals with or without ACC. Individuals with or without ACC are found within the same family and often within the same sibship. These observations support the hypothesis of a single genetic syndrome in which the constant manifestation is the motor and sensory neuropathy.
MESH: Adolescence-; Adult-; Child-; Child,-Preschool; Corpus-Callosum-pathology; Corpus-Callosum-radiography; English-Abstract; Neuropathies,-Hereditary-Motor-and-Sensory-diagnosis; Pedigree-
MESH: *Corpus-Callosum-abnormalities; *Magnetic-Resonance-Imaging; *Neuropathies,-Hereditary-Motor-and-Sensory-radiography
TG: Female; Human; Male
PT: JOURNAL-ARTICLE
AN: 90291330
UD: 9010
MEDLINE EXPRESS (R) 1990-1994 140 of 144
TI: Developmental abnormalities of the corpus callosum in schizophrenia.
AU: Swayze-VW 2d; Andreasen-NC; Ehrhardt-JC; Yuh-WT; Alliger-RJ; Cohen-GA
AD: Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242.
SO: Arch-Neurol. 1990 Jul; 47(7): 805-8
ISSN: 0003-9942
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
AB: Magnetic resonance imaging was used to evaluate neuroanatomical and neuropathologic abnormalities in a consecutive series of 140 patients with schizophrenia for comparison with normal controls. Partial agenesis of the corpus callosum, a rare neurodevelopmental abnormality, was found in two patients, one of whom also had a callosal lipoma. Evidence is presented suggesting that this finding represents an increased prevalence of partial agenesis in schizophrenia. The corpus callosum develops embryologically in intimate relationship to the hippocampal formation, fornix, septum pellucidum, and cingulate gyrus. In individuals with callosal agenesis, abnormalities also occur in the development of these limbic structures. Recent neuropathologic studies have suggested the occurrence of abnormal neurogenesis in the hippocampal formation and in the cingulate gyrus in schizophrenic patients. An increased prevalence of callosal agenesis and its related limbic abnormalities would further support investigation into neurodevelopmental abnormalities of these anatomical regions in schizophrenia.
MESH: Adult-; Limbic-System-abnormalities; Magnetic-Resonance-Imaging
MESH: *Corpus-Callosum-abnormalities; *Schizophrenia-pathology
TG: Case-Report; Female; Human; Male; Support,-Non-U.S.-Gov't; Support,-U.S.-Gov't,-P.H.S.
PT: JOURNAL-ARTICLE
CN: MH31593MHNIMH; MH40856MHNIMH; MH43271MHNIMH
AN: 90290383
UD: 9009
SB: AIM
MEDLINE EXPRESS (R) 1990-1994 141 of 144
TI: Unilateral photoconvulsive response in agenesis of the corpus callosum.
AU: Brinciotti-M; Matricardi-M; Trasatti-G
AD: Institute of Child Neuropsychiatry, University La Sapienza, Rome, Italy.
SO: Clin-Electroencephalogr. 1990 Apr; 21(2): 101-3
ISSN: 0009-9155
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
AB: An 11-year-old female presented with the unusual coexistence of self-induced photogenic epilepsy and an atypical epileptiform ictal EEG pattern evoked by intermittent photic stimulation. The EEG showed irregular 2.5-4 Hz spike-wave and polyspike-wave complexes, strictly localized on the left hemisphere, and associated with impairment of consciousness and myoclonic jerking of the contralateral side of the body. A computer tomographic scan showed agenesis of the corpus callosum. According to the literature on corpus callosum section in uncontrolled epilepsies, we hypothesize that in our patient the agenesis of the corpus callosum probably prevented the generalization of the ictal EEG pattern evoked by intermittent photic stimulation.
MESH: Child-; Corpus-Callosum-physiopathology; Epilepsy-physiopathology
MESH: *Corpus-Callosum-abnormalities; *Electroencephalography-; *Epilepsy-etiology; *Photic-Stimulation-adverse-effects
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 90242557
UD: 9008
MEDLINE EXPRESS (R) 1990-1994 142 of 144
TI: Craniosynostosis, agenesis of the corpus callosum, serve mental retardation, distinctive facies, camptodactyly, and hypogonadism.
AU: Lin-AE; Gettig-E
AD: Department of Medical Genetics, West Penn Hospital, Pittsburgh, Pennsylvania 15224.
SO: Am-J-Med-Genet. 1990 Apr; 35(4): 582-5
ISSN: 0148-7299
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
MESH: Abnormalities,-Multiple-genetics; Child,-Preschool; Infant-; Infant,-Newborn; Mental-Retardation; Syndrome-
MESH: *Abnormalities,-Multiple-diagnosis; *Corpus-Callosum-abnormalities; *Craniosynostoses-diagnosis; *Face-abnormalities; *Fingers-abnormalities; *Hypogonadism-diagnosis
TG: Human; Male
PT: JOURNAL-ARTICLE
AN: 90240245
UD: 9008
MEDLINE EXPRESS (R) 1990-1994 143 of 144
TI: The corpus callosum and cerebral speech lateralization [see comments]
CM: Comment in: Brain Lang 1990 Oct;39(3):471-4; discussion 475-81
AU: Lassonde-M; Bryden-MP; Demers-P
AD: Groupe de Recherche en Neuropsychologie, Universite de Montreal, Quebec, Canada.
SO: Brain-Lang. 1990 Feb; 38(2): 195-206
ISSN: 0093-934X
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
AB: In order to specify the callosal involvement in the establishment of cerebral lateralization, a dichotic listening task was administered to six subjects with congenital absence of the corpus callosum, two callosotomized patients, and two hemispherectomized patients. The acallosal subjects were also compared to six subjects matched for age, sex, and hand dominance as well as to six subjects also matched for IQ. Our findings indicate that language functions, as assessed by dichotic listening performance, are more strongly lateralized in callosal agenesis subjects than in IQ-matched normal controls. Our results also reveal that hemispherectomized patients typically show a strong ear-advantage favoring the ear contralateral to their remaining hemisphere. Callosotomized patients, on the other hand, show a more variable pattern of results that seems to be related to the postsurgical time interval. Finally, our findings suggest that there might be a relationship between IQ and lateralization in subjects with borderline or mild deficiency.
MESH: Adolescence-; Adult-; Corpus-Callosum-physiopathology; Corpus-Callosum-surgery; Dichotic-Listening-Tests; Intelligence-physiology; Phonetics-; Postoperative-Complications-physiopathology
MESH: *Attention-physiology; *Brain-Damage,-Chronic-physiopathology; *Corpus-Callosum-abnormalities; *Dominance,-Cerebral-physiology; *Speech-Perception-physiology
TG: Female; Human; Male; Support,-Non-U.S.-Gov't
PT: JOURNAL-ARTICLE
AN: 90213153
UD: 9007
MEDLINE EXPRESS (R) 1990-1994 144 of 144
TI: A disorder of axonal development, necrotizing myopathy, cardiomyopathy, and cataracts: a new familial disease.
AU: Lyon-G; Arita-F; Le-Galloudec-E; Vallee-L; Misson-JP; Ferriere-G
AD: Laboratory of Developmental Neurology, University of Louvain Medical School, Brussels, Belgium.
SO: Ann-Neurol. 1990 Feb; 27(2): 193-9
ISSN: 0364-5134
PY: 1990
LA: ENGLISH
CP: UNITED-STATES
AB: We report severe congenital encephalopathy and profound hypotonia associated with necrotizing myopathy, cardiomyopathy, and cataracts in 3 infants, including 2 sisters. Brain scans suggested agenesis of the corpus callosum. Neuropathological findings consisted of severe atrophy of the corpus callosum (not the usual agenesis with longitudinal callosal bundles), atrophy of the white matter, and absence of pyramidal tracts in the medulla. Multiple axonal swellings were present in the white matter and in Purkinje cells. Except for the corpus subthalamicum, gray matter structures were preserved. These findings are considered to be the expression of a primary disorder of axonal development leading to a reduction in interneuronal synaptic contacts. It is suggested that the anomaly may be due to an extension of the normal phenomenon of axonal elimination, related to a primary defect of the axonal cytoskeleton. The concept of a primary axonal disorder may also apply to other, mostly familial, conditions with progressive atrophy of the cerebral white matter and corpus callosum.
MESH: Atrophy-; Brain-Diseases-complications; Brain-Diseases-pathology; Cataract-complications; Corpus-Callosum-pathology; Heart-Diseases-genetics; Infant-; Muscular-Diseases-genetics; Pedigree-; Syndrome-
MESH: *Brain-Diseases-congenital; *Cataract-congenital; *Heart-Diseases-complications; *Muscular-Diseases-complications
TG: Case-Report; Female; Human
PT: JOURNAL-ARTICLE
AN: 90197137
UD: 9006
web contact: pietsch@indiana.edu